Steroid Medicines

Corticosteroids

Medicine
Brand Name

Dexamethasone alcohol
Maxidex

Dexamethasone Sodium phosphate
Decadron Phosphate

Prednisolone Acetate
Pred Forte, Econopret Plus, AK-Tate, Pred Mild, Econopred

Prednisolon Sodium phosphate
Inflamase Forte, AK-Pred, Hydeltrasol, Inflamase Mild, AK-Pred, Hydeltrasol

Fluoromethalone alcohol
FML

Medroxyprogesterone Acetate
Provera

Medrysone Alcohol
HMS

Rimexolone
Vexol

Loteprednol
 

Injected Corticosteroid Medicine

Medicine
Brand Name

Hydrocortisone
Hydrocortisone Sodium Succinate

Methylprednisolone sodium succinate
Solu-Medrol

Methylprednisolone acetate
Depo-Medrol

Triamcinolone Diacetate
Artisocort

Triamcinolone Acetonide
Kenalog

Dexamethasone Acetate
Decadron-LA

Dexamethasone sodium acetate
Decadron Phosphate

Betamethasone acetate and sodium phosphate
Celestone Soluspan

Nonsteroid Anti-Inflammatory Medicine

Drug type
Generic
Brand Name

Salicylates
Aspirin
Many

 
Diflunisal
Dolobid

Fenamates
Mefenamate
Pronstel

Indoles
Indomethacin
Indocin

 
Solindac
Clinoril

 
Tolmetrin
Tolectin

Phenylacetic acids
Diclofenac
Voltaren

Phenylalkanoic acids
Fenoprofen
Nalfon

 
Ketoprofen
Oridus

 
Piroxicam
Feldene

 
Flurbiprofen
Ansaid

 
Ketorolac
Toradol

 
Naproxen
Naprosyn

 
Ibuprofen
Motrin, Rufen, Advil, Nuprin

Pyrazolones
Phenylbutazone
Butazolidin

 
Oxyphenylbutazone
Tendearil, Osalid

Para-aminophenols
Acetaminophen
Many

Cox-2 inhibitors
Celecoxib
Celebrex

Medicines that Suppress the Immune System

(immunomodulatory therapy)

Medicines that suppress the body’s immune response can help save the sight of patients with some kinds of uveitis.

Antimetabolites

  • Azathioprine (Imuran)
  • Methotrexate (Rheumatrex)
  • Mycophenolate Mofetil (Cellcept)

T Cell Inhibitors

  • Cyclosporine (Sandimmune, Neoral)
  • Tacrolimus (Prograf)

Alkylating Agents

  • Chlorambucil (Leukeran)
  • Cyclophophamide (Cytoxan)

Biologics

  • Infliximab (Remicade)
  • Etanercept (Enbrel)
  • Interferon (Avonex)
  • Daclizumab (Zenapax)
  • Alefacept (Amevive)
  • Efalizumab (Raptiva)

Possible Side Effects of Treatment to Suppress the Immune System ► Possible Side Effects of Treatment to Suppress the Immune System ▼

The side effects described here will not affect everyone. Following are the most common and the less common side effects. We have not included those that are very rare and for that reason are very unlikely to affect you. If you do notice any effects which you think may be due to a medicine you are taking for uveitis, but which are not listed here, please discuss them with your doctor.

Side effects of Alkylating Agents (Cyclophosphamide/Chloramubcil)

Common side effects:

  • Temporary reduction in the production of blood cells. This can result in tiredness; an increased risk of bruising or bleeding and an increased risk of infection.
  • Feeling sick (nausea and vomiting)
  • Loss of appetite
  • Irritation of the bladder lining
  • Temporary hair loss

Less common side effects:

  • Temporary changes in the way your liver works
  • Sore mouth and taste change
  • Diarrhea
  • Changes in nails
  • Skin changes
  • Changes to the lungs. Tell your doctor if you notice coughing or breathlessness.
  • Cancer. There is a very small risk of developing a cancer after many years if this drug is taken long-term.
  • Changes to your heart. This is very uncommon with standard doses.

Additional information:

Always tell your doctor about any medicine you are taking.

Fertility: Your ability to become pregnant or father a child may be affected by taking this drug. Discuss fertility with your doctor before starting treatment.

Pregnancy: Cyclophosphamide may harm a developing fetus. Discuss this with your doctor.

Side effects of Antimetabolites

Methotrexate

Possible side effects:

  • Reduction in the production of blood cells. This can result in tiredness, increased risk of bruising or bleeding and an increased risk of infection.
  • Sore mouth and taste change
  • Diarrhea
  • Tiredness/feeling of weakness
  • Temporary skin changes
  • Kidney damage. This is not common with standard doses.
  • Inflammation of the cornea/feeling of grit in the eyes

Less common side effects:

  • Feeling sick (nausea and vomiting)
  • Blurred vision. Methotrexate may affect your sight. Tell your doctor about any eye pain or vision changes.
  • Hair loss
  • Sensitivity of the skin to sunlight
  • Rash
  • Changes to the lungs. Tell your doctor if you notice coughing or breathlessness.
  • Temporary changes in the way your liver works
  • Allergic reaction

Azathioprine

Possible side effects:

  • Reduction in the production of blood cells. This can result in tiredness, increased risk of bruising or bleeding and an increased risk of infection.
  • Feeling sick (nausea and vomiting)

Mycophenolate Mofetil

Possible side effects:

  • Dizziness
  • Tiredness
  • Headache
  • Feeling sick (nausea and vomiting)
  • Diarrhea
  • Rash

Side Effects of T Cell Inhibitors

Cyclosporine/Tacrolimus

Possible side effects:

  • Feeling sick (nausea and vomiting)
  • Diarrhea
  • Headache

You may also be at increased risk of infections or other illnesses. Call your doctor if you experience fever, chills, weakness; unusual bruising; swollen glands, skin growths, chest pain, more frequent or painful urination; swelling of the hands or feet; difficulty breathing, or upset stomach.

Side Effects of Biologics

Infliximab

Possible Side Effects:

  • Feeling sick (nausea and vomiting)

Call your doctor if you experience: fever, chills, headache, chest pain, cough, sore throat, unusual tiredness, stomach pain, unusual vaginal discharge or white patches in the mouth.

Less common side effects:

  • Diarrhea
  • Joint/muscle pain
  • Mental/mood changes
  • Changes in skin appearance
  • Painful urination
  • Increased urgency/frequency of urination
  • Easy bruising or bleeding

Etanercept

Possible Side Effects:

  • Colds
  • Cough
  • Headache
  • Feeling sick (nausea and vomiting)

Less common side effects:

Tell your doctor right away if you experience

  • Chest pain
  • Stomach pain
  • Difficulty breathing
  • Sore throat
  • Fever
  • Rash

Rare side effects:

Tell your doctor right away if you experience

  • Tingling of the hands or feet
  • Unsteadiness
  • Muscle weakness
  • Vision changes
  • Easy bruising or bleeding